IndraLab

Statements


USP16 is phosphorylated on S552. 4 / 18
10 | 4 4

sparser
"Cyclin-dependent kinase-1 (CDK1) was shown to phosphorylate USP16 at Ser552, retaining it in the nucleus and enabling proper cell cycle progression and proliferation [ xref ]."

sparser
"O-GlcNAcylation antagonizes CDK1-mediated USP16 Ser552 phosphorylation."

sparser
"Our previous study found that CDK1-mediated phosphorylation of USP16 at Ser552 occurs as cells enter the G 2 /M phase, which facilitates its nuclear localization and helps to remove uH2A for chromosome condensation when cells progress into the M phase ( xref , xref )."

sparser
"Therefore, we investigated whether O-GlcNAcylation antagonizes CDK1-mediated USP16 Ser552 phosphorylation."