IndraLab

Statements

IGF1R phosphorylates IRS1 on Y612. 6 / 6
1 | 3 1 1
reach
"IGF-IR phosphorylates IRS-1 on Y612, a PI3-K recruitment site, while EGFR preferentially phosphorylates IRS-1 on Y896, a Grb2 binding site."
20670944
signor
"Furthermore, IGF-1 stimulates tyrosine phosphorylation of insulin receptor substrate-1 (IRS-1) and IRS-2 and their association with the p85 subunit of phosphoinositide-3 kinase (PI3K)."
17827393
rlimsp
"IRS-1 is generally considered to be a unique substrate of IGF-IR, which phosphorylates IRS-1 at Y612."
25886138
reach
"Inhibition of IGF-IR by NVP-AEW541 decreased IGF-I-induced phosphorylation of Akt and IRS-1 (Y612)."
25886138
reach
"IRS-1 is generally considered to be a unique substrate of IGF-IR, which phosphorylates IRS-1 at Y612."
25886138
sparser
"IGF-IR phosphorylates IRS-1 on Y612, a PI3-K recruitment site, while EGFR preferentially phosphorylates IRS-1 on Y896, a Grb2 binding site."
20670944