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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

P38 decreases the amount of IRS1. 2 / 2

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"In the presence of insulin and the oxidant, the inhibition of p38 MAPK increased IRS-1 protein expression by 41% (p < 0.05) (XREF_FIG, left panel), thereby preventing 29% of the oxidant stress induced loss of IRS-1."

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"However, p38 inhibition did not prevent the loss of IRS-1 protein levels or insulin signaling to PKB in insulin resistant cells."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...