IndraLab

Statements

CTX3 inhibits USP9X. 2 / 2
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"As shown in XREF_FIG, CTX3 induced a decrease in the FAM fluorescence of FAM and DABCYL labeled A 40 in a concentration dependent manner, and maximal reduction in FAM fluorescence was noted when CTX3 was> = 120 nM."
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"As per the above findings, CTX3 disrupted the coralyne induced stem-loop MB structure and quenched the FAM fluorescence of A 12 -MB-A 12 irrespective of coralyne, hence two possibilities could be considered : (1) CTX3 bound to coralyne; and (2) CTX3 induced formation of the stem-loop MB structure."
28067855