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USP25 activates thiol-dependent ubiquitin-specific protease activity. 1 / 1

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"To examine whether the inhibitory effects of USP25 on SEV-induced type I IFN signaling is due to its deubiquitinase activity , wild-type USP25 ( USP25-WT ) and its mutants ( C178A and H607A ) lacking DUB activity were co-transfected with the promoter luciferase reporter plasmid of IFN-beta , IRF3 , NF-kappaB and ISRE , and the luciferase activity was detected ."

24260525

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IndraLab

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USP25 activates thiol-dependent ubiquitin-specific protease activity. 1 / 1

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