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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP25 activates thiol-dependent ubiquitin-specific protease activity. 1 / 1

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eidos

"To examine whether the inhibitory effects of USP25 on SEV-induced type I IFN signaling is due to its deubiquitinase activity , wild-type USP25 ( USP25-WT ) and its mutants ( C178A and H607A ) lacking DUB activity were co-transfected with the promoter luciferase reporter plasmid of IFN-beta , IRF3 , NF-kappaB and ISRE , and the luciferase activity was detected ."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...