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USP10 inhibits degradation. 2 / 2

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"These results suggested that LC3 is degraded by autophagy in both USP10-WT and USP10-KD cells with or without MG-132 treatment, and that USP10-KD does not inhibit autophagy-mediated degradation of LC3."

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"Notably, genetic or pharmacological inhibition of USP10 using Spautin-1 prominently decreased the stability of endogenous SKP2 protein (Fig. xref ), suggesting that USP10 inhibits the degradation of SKP2 in vivo."

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USP10 inhibits degradation. 2 / 2

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