IndraLab

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USP11 activates USP11. 2 / 3

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"Furthermore, we revealed that ERK1/2 phosphorylated USP11 at the Ser905 site, which promoted the cytoplasmic localization of USP11."

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"Hence, the methylation of USP11 appears to direct USP11 activity towards a particular stage of HR repair, namely DNA end-resection and RPA loading, rather than the formation of the BRCA1–PABL2–BRCA2 complex."

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IndraLab

Statements

USP11 activates USP11. 2 / 3

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