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Proteasome deubiquitinates PSMD14. 3 / 3
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"We can therefore conclude that Rpn11’s Ins-1 loop switches from an inhibitory closed state to an active β-hairpin conformation, allowing additional regulation of Rpn11 deubiquitination by Rpn11 in the[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"In line with this, knockdown of two components of the UPS, the ubiquitin ligase scaffolding protein Cul-1 and the proteasome-associated deubiquitinating protein Pad-1, leads to cell cycle reactivation and apoptosis in subsets of post-mitotic neurons (Staropoli and Abeliovich 2005)."
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"In parallel, the proteasome-associated deubiquitinating enzyme Poh1 liberates K63-Ub n from TRIM21, allowing unanchored K63-Ub n to serve as a signal to activate antiviral signaling pathways [131] ( F[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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