IndraLab

Statements

USP11 binds USP7 and PRC1. 6 / 6
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sparser
"USP7 and USP11 are bound to chromatin and form part of the PRC1 complex."
20601937
sparser
"Both USP7 and USP11 interact with PRC1 [ xref ], and these USPs might form a complex [ xref ], suggesting possible inter-USP regulation, the implications of which would be interesting for USP biology."
30897496
sparser
"Our data strongly suggest that USP7 and USP11 bind directly to several components of the PRC1 complex, as confirmed using purified recombinant proteins."
20601937
sparser
"In humans, USP7 and USP11 physically interact with members of PRC1 in vivo , such as Mel18, Bmi1 and Ring1."
29387079
sparser
"USP7 and USP11 associate with other PRC1 components."
20601937
sparser
"To assess whether USP7 and USP11 associate with bona fide PRC1 complexes, nuclear extracts from FDFs ( xref ) and 293T cells (not shown) were subjected to size exclusion chromatography on a Superose 6 10/300 column, and individual fractions were analysed by SDS–PAGE and immunoblotting."
20601937