IndraLab

Statements


ZUP1 leads to the ubiquitination of PCNA. 1 / 1
| 1

reach
"Remarkably, depletion of OTUB1 restored a pharmacologically disabled DSB response, indicating that targeting the OTUB1-E2 interaction might be an attractive route for the development of agents that bolster DSB repair.Another important example of the role played by DUBs in DNA repair relates to USP1, a DUB that modulates both FANCD2/FANCI and PCNA ubiquitylation [196], [197]."