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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP7 decreases the amount of CDKN2A. 1 / 2

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"The role of HAUSP in the epigenetic modification of proteins and regulation of gene expression is evident from its ability to deubiquitinate polycomb group RING finger 2 (MEL18) and BMI1 (components of the multiprotein polycomb repressive complex, PRC1), subsequently repressing the expression of the tumor suppressor p16INK4a, various homeotic genes and hormone dependent genes."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...