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USP7 decreases the amount of CDKN2A. 1 / 2

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"The role of HAUSP in the epigenetic modification of proteins and regulation of gene expression is evident from its ability to deubiquitinate polycomb group RING finger 2 (MEL18) and BMI1 (components of the multiprotein polycomb repressive complex, PRC1), subsequently repressing the expression of the tumor suppressor p16INK4a, various homeotic genes and hormone dependent genes."

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IndraLab

Statements

USP7 decreases the amount of CDKN2A. 1 / 2

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