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"Therefore, the neuroprotective effect of 3α-DIOL against PAC-induced painful neuropathological symptoms appears to be dependent on its ability to reverse to normal values decreased NF expression level, reduced CV and NAP peak amplitude in PAC-treated rat peripheral nerves.Moreover, our results also revealed that 3α-DIOL modulate differentially the expression of CNPase, NF200 and PGP9.5 genes."