IndraLab

Statements


USP7 activates Histone. 2 / 2
| 2

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"Although an indirect correlation between USP7 and the metastasis of gastric cancer has been shown previously by altering the levels of USP7 mediated histone demethylase PHF8 (Li et al., 2017), our study demonstrated the direct correlation between USP7 enzyme activity and cancer cell migration ability in a p53 independent manner for the first time."

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"The present study evaluated whether USP7 also mediates histone acetyltransferase Tat-interactive protein 60 (Tip60) in the development of ALI inflammation."