IndraLab
Statements
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"In an attempt to identify other novel proteins that interact with MDM2, we performed a co-precipitation of proteins bound to a biotinylated MDM2 peptide attached to streptavidin beads in which ribosomal protein S3 (RPS3) was one of the two proteins captured, and subsequently led to the discovery that RPS3 also interacts with p53 to protect it from MDM2-mediated ubiquitination."