IndraLab

Statements

USP11 leads to the ubiquitination of SPRTN. 3 / 3
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reach
"USP11 depletion impairs SPRTN deubiquitination and promotes SPRTN auto-proteolysis in response to formaldehyde induced DPCs."
33567341
reach
"These observations show that depletion of USP11 and VCPIP1 inhibits SPRTN deubiquitination, but in contrast to previous reports, monoubiquitination does not restrict SPRTN access to chromatin."
33567341
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"Similarly, USP11 depletion in HCT116 inhibited SFB-SPRTN deubiquitination (XREF_FIG B, lane 4) compared with negative control (XREF_FIG B, lane 2) upon formaldehyde treatment, suggesting that USP11 depletion inhibits SPRTN deubiquitination upon DPC induction."
33567341