IndraLab

Statements


EGFR bound to AREG is active. 3 / 3
3 |

"Remarkably, three members of the epidermal growth factor (egf) family (ereg, areg, and epgn) showed increased expression that was associated with elevated epidermal activation of the egf receptor (egfr) and stat3, a downstream effector of egfr signaling."

"The epidermal growth factor receptor (EGFR) mediates the actions of a family of bioactive peptides that include epidermal growth factor (EGF) and amphiregulin (AR)"

"ErbB ligands include: EGF, transforming growth factor (TGF)_, and amphiregulin which only bind ErbB1"