IndraLab

Statements


STUB1 decreases the amount of ATXN3. 2 / 4
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"Also, consistent with effects in non neuronal cells, both CHIP and Parkin decreased Q78 ataxin-3 levels in MN-1 neuronal cells but Mdm2 did not (XREF_FIG)."

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"As a result, silencing of CHIP significantly increases the amount of Atx3 (XREF_FIG), suggesting that CHIP may down-regulate the Atx3 level."