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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

MAP3K5 methylated on R89 inhibits MAP3K5. 1 / 1

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"In summary, H 2 O 2 -induced ASK1 activity can be inhibited by PRMT5 methylation of ASK1 at Arg 89, which in turn promotes interaction between ASK1 and Akt and enhances phosphorylation of ASK1 at Ser 83, which inhibits endothelial cells apoptosis."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...