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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

DCAF10 binds CUL4A, DDB1, and OTUD1. 1 / 1

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"Interestingly, two molecules (DDB1 and DCAF10) in the MS data attracted our attention because DCAFs function as substrate receptors for the CUL4‐DDB1 ubiquitin ligase, [ xref ] which was identified as mediating the ubiquitination of MCL1 in a recent study. [ xref ] We next performed co‐IP assays and showed that CUL4A, DDB1, and DCAF10 associated with wild‐type OTUD1, but not OTUD1 C320A , in vivo (Figure xref – xref )."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...