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USP14 decreases the amount of AR-V7. 2 / 2

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"Knockdown USP14 could suppress the expression of AR-FL and AR-V7 in protein levels, but no effect was seen on mRNA levels."

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"Western blot and CCK8 assays showed that the overexpression of USP14/USP22 not only reversed the downregulation of AR-V7 level by nobiletin to a certain extent, but also partly weakened nobiletin-induced inhibition of the CRPC cell viability (Fig. 5I–L)."

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IndraLab

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USP14 decreases the amount of AR-V7. 2 / 2

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