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5-(5,6-dimethoxy-1-benzimidazolyl)-3-[[2-(trifluoromethyl)phenyl]methoxy]-2-thiophenecarboxamide inhibits MYD88. 1 / 1

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"In addition, GW843682X treatment for 12 to 24 h induced cell death and down-regulated MyD88, but neither of these roles contributed to the down-regulation of TNF-alpha, as TNF-alpha gene expression was up-regulated at 1 h. Furthermore, GW843682X inhibited Pam3CSK4 induced activation of ERK and NF-kappaB, which contributed to Pam3CSK4 induced up-regulation of TNF-alpha."

24205328

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IndraLab

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5-(5,6-dimethoxy-1-benzimidazolyl)-3-[[2-(trifluoromethyl)phenyl]methoxy]-2-thiophenecarboxamide inhibits MYD88. 1 / 1

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