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USP22 increases the amount of VIM. 3 / 3
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"Molecular analysis of the tumor tissues showed that USP22 knockdown reduced the levels of cyclin D2, Akt phosphorylation, vimentin, and Bcl-2, whereas upregulated the expressions of E-cadherin, Bax, and cleaved (cl)-caspase-3, which confirmed in vitro findings."
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"AP4 down-regulation partially reversed the increases in N-cadherin and vimentin expression levels induced by USP22 up-regulation; however, no changes in USP22 expression levels were observed."
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"Western blot analysis showed that USP22 knockdown in H1650 suppressed expression of the mesenchymal markers N-cadherin and vimentin and increased expression of the epithelial markers E-cadherin and al[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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