IndraLab

Statements


CYLD acetylates MTs. 3 / 3
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"The finding that CYLD colocalizes with HDAC6 in the midbody between bundles of acetylated MTs in both keratinocytes and melanoma cells, prompted us to investigate the rate of cytokinesis in these cells."

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"CYLD induces acetylation of alpha-tubulin and stabilization of MTs."

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"These results suggest that CYLD colocalizes mainly with acetylated MTs in the perinuclear region, and this localization is constitutive in CYLD transduced melanoma cells, whereas in primary mouse keratinocytes or primary human melanocytes (XREF_SUPPLEMENTARY) it is induced after TPA treatment or exposure to UV light."