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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

SOS1 binds CBL, LAT, and GRB2. 1 / 1

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"One such mechanism involves cooperative interactions between LAT, SOS1, c-Cbl, and GRB2 molecules, in which multiple binding sites on LAT and SOS1 or c-Cbl for the SH2 and SH3 domains of GRB2 enable oligomerization of LAT-associated signaling molecules xref ."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...