IndraLab

Statements


| 2

sparser
"The two domains may become constrained by the simultaneous binding of Uch37 and hRpn13’s Pru domain to different ubiquitin moieties within a chain."

sparser
"hRpn13’s PRU binds its C-terminal Uch37-binding domain, which reduces the exposure of its ubiquitin binding surface and in turn, its affinity for ubiquitin ( xref )."