IndraLab

Statements


WP1130 activates USP14. 2 / 2
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"Trypsin derived peptides from both lanes of this region in the gel were subjected to mass spectrometric analysis, which identified USP14 only in samples treated with biotinylated WP1130 but not the inactive analog."

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"WP1130, a small molecule inhibitor of cellular Deubiquitinases (DUBs), was found to inhibit replication of murine noroviruses in murine macrophages, and human norovirus in a replicon system by targeting the cellular DUB USP14 [XREF_BIBR]."