IndraLab

Statements

SPATA2 binds RNF31 and CYLD. 4 / 4
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sparser
"Importantly, the HOIP-SPATA2-CYLD complex is formed at the TNFR complex, whereas OTULIN does not translocate with LUBAC to the TNFR complex [ xref , xref , xref ]."
28446710
reach
"Importantly, the HOIP, SPATA2, and CYLD complex is formed at the TNFR complex, whereas OTULIN does not translocate with LUBAC to the TNFR complex [XREF_BIBR, XREF_BIBR, XREF_BIBR]."
28446710
sparser
"To characterize the interaction of SPATA2 with CYLD and HOIP further, we expressed various deletion mutants of SPATA2 with a GFP tag."
27545878
sparser
"Strikingly, the extended SPATA2 fragment formed a trimeric complex with CYLD and HOIP that eluted with an MW of 170 kDa, indicative of a stable 2:2:2 complex ( xref G, red, green, and orange curves; see xref for details on stoichiometry calculation)."
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