IndraLab

Statements

USP4 deubiquitinates PDPK1. 3 / 3
1 | 2
reach
"USP4 deubiquitinates PDK1 and co-localizes at the plasma membrane."
22347420
reach
"In addition, the closely related USP15, which shares 61% amino acid sequence identity with USP4 XREF_BIBR, had no effect on Ub-PDK1 levels, further suggesting that the ability of USP4 to deubiquitinate PDK1 is specific."
22347420
ubibrowser
"By screening a library of ubiquitin proteases, we further identify the Ubiquitin-Specific Protease 4 (USP4) as an enzyme that removes ubiquitin from PDK1 in vivo and in vitro and co-localizes with PDK1 at the plasma membrane when the two proteins are overexpressed, indicating direct deubiquitination."
22347420