IndraLab

Statements

Ubiquitin binds USP30. 2 / 3

| 2

sparser

"This explains complications with estimating USP30K M values for monoubiquitin substrates xref , xref , orK d values for the interaction between inactive USP30 and fluorescent ubiquitin ( xref , xref ); similar substrates bind other (inactive) USPs with nM to low µM affinities xref , xref ( xref )."

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➶

sparser

"The USP30 diubiquitin complex structure ( xref , xref ) explains this preferential binding, and reveals how the proximal ubiquitin interacts with USP30 in three areas ( xref ):"

28945249

INDRA sources:

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IndraLab

Statements

Ubiquitin binds USP30. 2 / 3

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