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USP15 activates TGF-beta pathway. 2 / 2
| 2

eidos
"USP15 has previously been shown to activate the TGF-beta pathway through deubiquitination of the type I TGF-beta receptor and receptor-activated SMAD proteins ( 26,27 ) ."

eidos
"38 , 39 , 40 , 41 For example , USP15 upregulates the TGF-beta pathway to promote cell proliferation in glioblastoma pathogenesis ."