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Naltrexone inhibits ITCH. 7 / 7
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"The spontaneous scratching of NC mice with dermatitis was inhibited by distraction and the opioid antagonist naltrexone, suggesting that the scratching is itch associated response."
11154860
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"A placebo controlled study in 18 patients with chronic pruritic associated with a variety of disorders showed that naltrexone, applied topically, significantly decreased itch."
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"As a third-line option, (3) opioid antagonists (naloxone, nalmefene, naltrexone) have been found to reduce itch severity in patients with PBC [298, 302–304]."
19603170
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"As a thirdline option, (3) opioid antagonists (naloxone, nalmefene, naltrexone) have been found to reduce itch severity in patients with PBC [298, [302] [303] [304] ."
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"Persistent itch in dialysis patients was relieved by naltrexone [317], and pruritus in post-Caesarean section patients with epidural morphine was attenuated by naloxone or nalbuphine [209], suggesting[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
9437729
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"Naloxone and naltrexone also suppress the itch sensation in patients with chronic cholestasis, chronic renal failure and atopic dermatitis (Bergasa et al., 1992; Peer et al., 1996; Metze et al., 1999)[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
11821035
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"As a third-line option, (3) opioid antagonists (naloxone, nalmefene, naltrexone) have been found to reduce itch severity in patients with PBC [XREF_BIBR, XREF_BIBR - XREF_BIBR]."
19603170