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phosphosite cbn pc11 biopax bel_lc signor biogrid tas lincs_drug hprd trrust | geneways tees isi trips rlimsp medscan sparser reach

P14_3_3 binds BRAF and RAF1. 2 / 2
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"Although this appears to contradict our observation that dephosphorylation does not disrupt the complex, because 14-3-3 binds to BRAF and CRAF in a phosphorylation-dependent manner, we presume that 14-3-3 protects these sites from dephosphorylation."
"Further studies will be required to investigate how the differential and dynamic regulation of 14-3-3 binding to the conserved C-terminal sites in C-RAF and B-RAF ( Hekman et al., 2004 ) affects bindi[MISSING/INVALID API KEY: limited to 200 char for Elsevier]"