IndraLab

Statements

USP14 binds TRIM11. 9 / 9
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"This, along with the PSMD2-TRIM11 interaction, raised the possibility that TRIM11 might also bind to USP14."
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"TRIM11 interacts with USP14."
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"This, along with the PSMD2-TRIM11 interaction, raised the possibility that TRIM11 might also bind to USP14."
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"The TRIM11-USP14 interaction is likely to be direct, as shown by an in vitro pull-down assay using purified recombinant proteins (Fig.  xref )."
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"Next, we delineated the structural determinants of the TRIM11-USP14 interaction."
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"Structural determinants of the TRIM11-USP14 interaction."
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"The current study reveals a distinct proteasome-regulatory pathway based on stableprotein protein interaction, in which TRIM11 binds to USP14 precluding its recruitment to the RP subcomplex of the proteasome."
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"Indeed, Flag-TRIM11 expressed in HCT116 cells interacted with endogenous USP14, based on a co-IP assay with anti-Flag antibody and a reciprocal assay with anti-USP14 antibody."
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"The current study reveals a distinct proteasome-regulatory pathway based on stable protein–protein interaction, in which TRIM11 binds to USP14 precluding its recruitment to the RP subcomplex of the proteasome."
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