IndraLab

Statements

ABL1 phosphorylates OTULIN. 4 / 4
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"The c-Abl-dependent OTULIN phosphorylation in response to genotoxic treatments relies on DNA-PK but not ATM or ATR."
32770022
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"ABL1-dependent OTULIN phosphorylation promotes genotoxic Wnt/β-catenin activation to enhance drug resistance in breast cancers."
32770022
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"The potential role of c-Abl-dependent OTULIN phosphorylation in regulating genotoxic NF-κB signaling warrant further investigation."
32770022
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"We showed that ABL1 (ABL proto-oncogene 1)-dependent phosphorylation of OTULIN (OTU deubiquitinase with linear linkage specificity) upon DNA damage drives β-catenin activation which promotes drug resistance in triple-negative breast cancer."
33241111