Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

ATP13A2 decreases the amount of TSC2. 1 / 1

| 1

➶

reach

"Accordingly, we found for the first time that ATP13A2 downregulation decreases TSC2 levels, by a mechanism dependent on MYCBP2 induced ubiquitination, which in turn activates mTORC1, inhibits TFEB translocation to the nucleus and compromises TFEB mediated transcription of SYT11."

27278822

Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...