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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

ATM phosphorylates ASXL1. 3 / 3

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"Upon DNA damage RNF8 detects motifs in mediator of DNA damage checkpoint protein 1 (MDC1) previously phosphorylated by ATM and performs K63-linked monoubiquitylation of histones H2A and H2AX."

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"One of the key initiating steps in the damage response is the phosphorylation of human ssDNA binding protein 1 (hSSB1) by ATM."

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"One of DDR proteins is mediator of DNA-damage checkpoint protein 1 (MDC1), which is phosphorylated by ATM and binds γH2AX."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

ATM phosphorylates ASXL1. 3 / 3

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