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"Lasted studies have reported that snoRNAs could directly bind to functional protein to promote tumorigenesis.48, 49 Therefore, we inferred that USP34 or SNORA70B might bind WNT pathway–related protein to activate it.In general, we identified a six‐snoRNA signature as an independent and specific indicator to diagnose and predict prognosis of ccRCC patients, providing a prospective diagnostic and prognostic biomarker and potential therapeutic targets for ccRCC."