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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

TP53-L344P increases the amount of CDKN1A. 1 / 1

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"Dox-induced expression of p53-R273H or p53-L344P mutants failed to increase p21 expression as assessed by RNA-FISH measurements of the percentage of cells with active p21 transcription sites (Figure 4B), by p21 nascent RNA levels (Figure 4C, blue), and by the number of p21 RNA molecules per cell (Figures 4D and S4H)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...