A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.



phosphosite cbn pc11 biopax bel_lc signor biogrid tas lincs_drug hprd trrust | geneways tees isi trips rlimsp medscan sparser reach

Modified TP53 decreases the amount of mutated TP53. 2 / 2
| 2
"Loss of p53 in mice increased the frequency of HR [XREF_BIBR], and expression of p53 mutants in human Leukemia cell line led to a noticeable increase in HR whereas wild type p53 (wtp53) decreased HR frequency [XREF_BIBR], indicating p53 is required for HR-inhibition."
"31 The overexpression of wild-type TP53 decreased in vitro migration and invasion of the mutant TP53 expressing cells (U373-MG; XREF_FIG)."