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Modified TP53 decreases the amount of mutated TP53. 2 / 2
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"Loss of p53 in mice increased the frequency of HR [XREF_BIBR], and expression of p53 mutants in human Leukemia cell line led to a noticeable increase in HR whereas wild type p53 (wtp53) decreased HR frequency [XREF_BIBR], indicating p53 is required for HR-inhibition."

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"31 The overexpression of wild-type TP53 decreased in vitro migration and invasion of the mutant TP53 expressing cells (U373-MG; XREF_FIG)."