IndraLab
Statements
reach
"Collectively, these data indicate that dysregulated chemokine expression caused by USP12 downregulation, as exemplified by CXCL1 and CCL2, is important for the development of immune-suppressive TME.To validate whether the role of USP12 on TME reprogramming has pathological relevance in human NSCLC, we investigated the relationship between TAMs and USP12 expression in human NSCLC cohorts."