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USP12 increases the amount of Chemokine. 1 / 1
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"Collectively, these data indicate that dysregulated chemokine expression caused by USP12 downregulation, as exemplified by CXCL1 and CCL2, is important for the development of immune-suppressive TME.To validate whether the role of USP12 on TME reprogramming has pathological relevance in human NSCLC, we investigated the relationship between TAMs and USP12 expression in human NSCLC cohorts."