IndraLab

Statements


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reach
"Recently, Duhme et al. demonstrated that altered C-linker interaction in hyperpolarized activated ion channel HCN4 is associated with familial TBS and AF, indicating that funny channel dysfunction contributes to the development of atrial tachyarrhythmias [XREF_BIBR]."

sparser
"HCN4 encodes for the cardiac pacemaker channel and HCN4 mutations are associated with familial sinus bradycardia and AF."

sparser
"Therefore, we sought to determine if genetic variation in the coding region of the HCN4 gene is associated with AF."