IndraLab

Statements

RB1 phosphorylated on S780 is transcriptionally inactive. 4 / 4
2 2 |
bel
"PD 0183812 blocks phosphorylation on pRb in tumor cells PD 0183812 inhibits phosphorylation of pRb at serine 780"
11278443
bel
"TGF-beta1 increased retinoblastoma protein phosphorylation at both Ser807/811 and Ser780. Silencing Nox4 prevented TGF-beta1-mediated retinoblastoma protein phosphorylation, proliferation, and cell hypertrophy. TGF-beta1 also increased phosphorylation of eukaryotic translation initiation factor 4E binding protein-1 at Thr37/46, and this was likewise blocked by silencing Nox4"
17369289
bel
"TGF-beta1 increased retinoblastoma protein phosphorylation at both Ser807/811 and Ser780. Silencing Nox4 prevented TGF-beta1-mediated retinoblastoma protein phosphorylation, proliferation, and cell hypertrophy. TGF-beta1 also increased phosphorylation of eukaryotic translation initiation factor 4E binding protein-1 at Thr37/46, and this was likewise blocked by silencing Nox4"
17369289
bel
"PD 0183812 blocks phosphorylation on pRb in tumor cells PD 0183812 inhibits phosphorylation of pRb at serine 780"
11278443