IndraLab

Statements


CXXC1 methylates KCNQ1. 4 / 4
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sparser
"In skeletal muscle, CpG sites in CDKN2A , DUSP9 , HNF4A , HHEX , KCNQ1 , KLF11 , PPARGC1A and SLC30A8 were differentially methylated."

sparser
"In line with this, though at some distance from the sites described above, we observed both increased methylation of six CpG sites in KCNQ1 (4 CpGs Chr16:2464845–2465103, TSS1500, ∆beta 0.061-0.104, two CpG sites Chr: 16:2828778, ∆beta 0.08, Chr16:2858355, ∆beta 0.10) and decreased methylation of FTO (∆beta −0.113, Chr16: 54025348) before weight loss."

sparser
"Here we report increased methylation of APBA2, APBA3, GATA4, KCNQ1, MCF2, NINJ2 and TAAR5 at gene-specific CpG sites in female BPD blood samples compared to controls."

sparser
"A DMR was identified in one of the type-2 diabetes genes ( PROX1) and differential methylation of the six CpG sites in KCNQ1 were validated by pyrosequencing (see later)."