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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

TNFAIP3 inhibits SETBP1. 1 / 1

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"A novel phenomenon was noted in the present study; in TNFAIP3 deficient HT-29 cells, a large number of SEB carrying endosomes were observed in HT-29 cells, but few SEB + endosome and lysosome were observed; the phenomenon indicates the lacking TNFAIP3 prevents the SEB carrying endosome from fusing the lysosome in the HT-29 cells since TNFAIP3 can tether endosomes to lysosomes XREF_BIBR; or in other words, TNFAIP3 is required in the endosome and lysosome fusion."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...