IndraLab

Statements


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sparser
"The observations that OTULIN mutation negatively impacts vessel development and that OTULIN interacts with dishevelled (DVL) 2, a Wnt signaling adapter, suggested that linear ubiquitination could be involved in Wnt signaling."

sparser
"The interaction of OTULIN with a key component Dishevelled (Dvl/Dsh) mediates this regulation through the Wnt signalling cascade."

sparser
"Moreover, a reported interaction of OTULIN and dishevelled‐2 (DVL2) could be confirmed, suggesting a role of Met1‐linked ubiquitination in Wnt signalling xref , xref ."