IndraLab

Statements

reach
"The results indicated that USP1 knockdown significantly inhibited the proliferation of MHCC97H and SK‐Hep‐1 cells (Figure 10G)."
32951278
reach
"The numerous data demonstrate that inhibition of USP1 suppresses the proliferation and viability of malignant cells, sensitizes them to radiation and increases their sensitivity to various chemo- therapeutic agents, which opens up new opportunities for combined therapy of malignant neoplasms."
37331010
eidos
"Similarly , pharmacological inhibition of USP1 by SJB3-019A significantly repressed cell proliferation and triggered B-ALL cell apoptosis ."
33390793
reach
"Conversely, ectopic USP1 expression in mesenchymal stem cells stabilized ID proteins, inhibited osteoblastic differentiation, and enhanced proliferation."
21925315
reach
"In addition, inhibition of USP1 decreased PC proliferation and promoted response to therapeutic agent enzalutamide in a KDM4A dependent manner."
32133742
reach
"USP1 knockdown inhibited cell proliferation by more than 2-fold within 72h of seeding and showed a simultaneous increase in caspase activity."
32947124
reach
"The supportive evidence is as follows : (i) USP1 knockdown decreased PC cell proliferation in vitro and tumorigenesis in vivo, and promoted the response to therapeutic agent enzalutamide; and (ii) inhibition of USP1 sensitized cancer cells to therapeutic agent enzalutamide, whereas this effect was blunted by overexpression of KDM4A."
32133742
reach
"USP1 overexpression enhanced the migration and invasion of CRC cells, while its silencing attenuated the cell vitality and proliferation, induced the apoptosis of CRC cells."
35579161
reach
"USP1 depletion abolished cellular proliferation and attenuated glycolytic metabolism."
36912760
reach
"Gene silencing of USP1 by lentivirus effectively inhibits proliferation and invasion of human osteosarcoma cells."
27840911
eidos
"Notably , downregulation of USP1 could inhibit cell proliferation and promote apoptosis in a variety of solid tumors 9,11,12 ."
33390793
reach
"Consistent with increased p21, USP1 knockdown reduced U2-OS cell proliferation."
21925315
eidos
"Recent studies have demonstrated that USP1 inhibition induced apoptosis and suppressed cell proliferation in acute myeloid leukemia ( AML ) and MM cells 12 , 13 ."
33390793
eidos
"USP1 knockdown or ML-323 treatment decreases cell proliferation , and reduces expression of proliferating cell nuclear antigen ( PCNA ) , cyclin D1 and cyclin E1 ."
32951278
reach
"USP1 knockdown similarly reduced proliferation in HOS, SAOS, and SJSA, but not MG-63 osteosarcoma cells."
21925315
reach
"Similarly, pharmacological inhibition of USP1 by SJB3-019A significantly repressed cell proliferation and triggered B-ALL cell apoptosis."
33390793
reach
"Overexpression of USP1 promoted cell proliferation, apoptosis, migration and invasion, and decreased cell chemo-sensitivity; however, it could be partially reversed via the overexpression of miR-192-5p in osteosarcoma cell lines."
29731868