IndraLab

Statements

Mutated NGF activates NTRK1. 3 / 3
| 3
reach
"During retinal degeneration due to glaucoma or optic nerve transection, treatment with a mutant NGF that only activates TrkA, or with a biological response modifier that prevents endogenous NGF and pro NGF from binding to p75 (NTR) affords significant neuroprotection."
20943663
reach
"Our data helps to explain the molecular mechanisms involved in TrkA downstream activation mediated by WT and mutant NGF, providing new insights to novel development to trigger each signaling pathway specifically."
32497034
reach
"Treatment with a mutant NGF that only activates TrkA affords significant neuroprotection."
25250333