IndraLab

Statements


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sparser
"CALM3 has now been associated with CPVT and both CALM1 and CALM3 mutations evoke arrhythmogenic Ca disturbances via ryanodine receptor 2 dysregulation [ xref ]."

sparser
"Several reports exist of mutations in the CALM1CALM3 genes, each encoding the ubiquitous Ca 2+ sensing protein calmodulin, in relation to LQTS and sinus bradycardia (Table xref and Table xref )."

sparser
"Although it is difficult to compare the frequencies of different hits directly due to differences in protein target abundance and efficiency of detection, these findings are consistent with CaM1 and CaM3 interacting with a number of apical complex proteins, including MyoH."

sparser
"In Table xref and Table xref , we, like others ( xref , xref ), used LQT14–LQT16 in relation to mutations in CALM1CALM3 ."

sparser
"The expression of calmodulin 1–3 (CALM1CALM3), ER chaperone calreticulin (CALR), calnexin (CANX), voltage gated calcium influx channel Cav1.2, calcium efflux channel plasma membrane Ca2+ ATPase (PMCA[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

sparser
"CALM1‐3 encoded by three independent genes ( Calm1Calm3 ) express the identical calmodulin (CaM) proteins, [ xref ] which possess intracellular Ca 2+ ‐binding functions. [ xref ] To assess the exact binding site of alnustone on CaM, we carried out molecular docking."

sparser
"Interestingly, analysis of the STRING database () suggests that there is an interaction network involving Slc27a2, SCD, Lep, and Adipog, as well as between TRPV4 and its potential interacting partners Calm3 and Calm1."

sparser
"Ca 2+ acts as a second messenger and an early response factor in the heat stress response by binding to CAM1 and CAM3 and potentially influencing HSFA2 gene expression."