IndraLab

Statements

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"Downregulation of USP13 significantly attenuated the invasiveness of 143B cells, while overexpression of USP13 promoted the invasiveness of HOS cells by using the transwell invasion assay (Fig. 2a, b)."
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"USP13 promotes breast cancer cell migration, invasion and lung metastasis through Twist1."
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"USP13 promotes melanoma cell invasion by stabilizing the microphthalmia-associated transcription factor."
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"We further demonstrated that USP13 obviously promoted OS cells invasion using a 3D tumor spheroid cell-invasion assay (Fig. 2c, d)."
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"USP13 knockdown prominently suppressed MGC-803 cell migration and invasion."
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"USP13 knockdown prominently suppressed MGC-803 cell migration and invasion ."
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"Next, USP13 knockdown prominently reduced the proliferation, epithelial-mesenchymal transition (EMT), migration, and invasion of Hep3B and Huh7 cells, while USP13 overexpression enhanced these biological behaviors of HepG2 and LO2 cells."
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"Although USP13 assumes an antiviral role during the pathogenesis of SARS-CoV-2 (Ravindran et al., 2022), some contend that in specific scenarios, USP13 not only fails to impart antiviral effects but instead stimulates viral invasion."
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"High expression of USP13 promotes the migration and invasion of tumors such as breast cancer through Twist1 (79)."
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"USP13 promotes migration and invasion of GC cells by maintaining the stability of Snail."
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"USP13 has been shown to upregulate fatty acid synthase (FASN) to promote the proliferation of SCLC cells and Twist-related protein 1 (Twist1) to promote the migration and invasion of breast cancer cells, while it inhibits cell proliferation via downregulation of glycolysis in oral squamous cell carcinoma (47,48)."
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"Finally, Snail knockdown significantly blocked USP13-induced SGC-7901 cell migration and invasion."
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"Meanwhile, exogenous overexpression of FLAG-tagged USP13 in H460 cells significantly promoted cell invasion ( Figure S1 F)."
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"30 To further confirm the invasion-promoting role of USP13, we established a spontaneous metastasis model, in which subcutaneous growth of a highly invasive lung cancer cell line (889DTC) leads to the[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"We found that the effect of USP13 in promoting the migration and invasion capacities of breast cancer cells can at least partly be achieved through its regulation of Twist1, while Twist1 can inhibit the transcriptional activity of USP13."
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"For example, USP13 stimulates melanoma cell invasion,20 drives ovarian cancer metabolism,21 and promotes the proliferation of glioma stem cells,22 which demonstrates the oncogenic roles of USP13 in these cancers."
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