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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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USP7 deubiquitinates Poleta. 5 / 5

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"USP7 deubiquitinates and stabilizes Poleta."

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"Conversely, overexpression of USP7, directly reducing the polyubiquitination of Poleta mediated by Mdm2, also leads to Poleta stability."

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"USP7 can directly deubiquitinate and stabilize Poleta in cells."

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"An in-depth analysis revealed that USP7 deubiquitinates and stabilizes Poleta through direct protein protein interaction."

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"As shown in XREF_FIG, the levels of polyubiquitinated Poleta decreased gradually in a dose dependent manner by increasing the concentration of recombinant USP7, suggesting that deubiquitination of Poleta is mediated by USP7."

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USP7 deubiquitinates Poleta. 5 / 5

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